-
Advanced Preservation Reagents to Power Immuno-Oncology and Multiomics Research, July 24, 2024
-
This webinar showcases two sets of data powered by this novel cell preservation solution. First, learn how it enabled researchers to explore the tumor microenvironment (TME) and its influence on immunomodulatory agents. A novel approach to examine immune responses in the TME with small tumor samples will be presented. This approach has now helped uncover the balance of PD-1 expression between tumor-infiltrating effector cells and regulatory T (Treg) cells as a biomarker for evaluating the effects of PD-1/PD-L1 blockade immunotherapy. The second set of data will walk you through a step-by-step approach for conducting single-cell multiomics studies to generate high-quality data with preserved samples. Learn how to preserve and ship your samples for up to 72 hours at 4°C and still generate RNA-seq, CITE-seq and TCR/BCR single-cell data with confidence.
-
-
Unveiling Immune Biology with Epigenomics and Image-Based Spectral Sorting, June 25, 2024
- Multimodal profiling can help us gain new insights about immune biology. This webcast describes an innovative, multimodal approach to T cell functional phenotyping by combining spectral image-enabled cell sorting with single-cell multiomics covering whole transcriptome and epigenomic profiling using an ATAC-seq assay. This multimodal approach was used to analyze ~200,000 T cells sorted from an in vitro model of T cell activation to reveal in-depth molecular and cellular dynamics data about T cell activation and biology.
-
Single-Cell Plant Technologies Webinar, May 07, 2024
-
In this webinar, Dr. Carolin Grones addresses the challenges of single-cell transcriptomics applied to plant tissues while proposing a novel single-nuclei approach to deliver more robust and high-quality data, thanks to the BD Rhapsody™ Single-Cell Analysis System.
-
-
Immunology out of its comfort zone: single-cell insights with spectral flow cytometry and multiomics, March 27, 2024
- This webcast presents an integrative approach using real-time imaging, spectral flow cytometry and Cellular Indexing of Transcriptomes and Epitopes by sequencing (CITE-seq) to perform high-dimensional, multimodal analyses of human T regulatory (Treg) cells. This combinatorial approach reveals different subsets of Tregs while uncovering distinct, heterogeneous proteomic and genomic signatures associated with naïve, activated, and memory Treg cell populations. This approach now offers a novel, multimodal tool set with which to drive the next generation of immunology research.